Brain Tumour Epidemiology in Austria and the Austrian Brain Tumour Registry

............................................................................................................ 3 Zusammenfassung............................................................................................. 4 Definition of Epidemiological Terms .................................................................... 5 Background....................................................................................................... 6 1. Cancer control and cancer registries........................................................................... 6 2. Primary Brain Tumours........................................................................................... 7 Summary of Results – Austrian Brain Tumour Registry........................................... 9 1. Set-up of a population-based brain tumour registry in Austria.......................................... 9 2. Population-based epidemiology and tissue-based analyses...........................................12 3. Neuropathological characterisation of new tumour entities..............................................15 4. Increasing use of molecular markers in brain tumour epidemiology.................................18 5. Outcome Surveillance........................................................................................... 20 Added Value & Future Perspectives.................................................................... 26 Peer-reviewed publications.................................................................................40 1. The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry. Wöhrer et al, Journal of Neurooncology 2009, 95:401–11............... 40 2. Incidence of atypical teratoid/rhabdoid tumours in children: a population-based study by the Austrian Brain Tumour Registry, 1996–2006. Wöhrer et al, Cancer 2010, 116:5725–32......67 3. Embryonal Tumour with Abundant Neuropil and True Rosettes (ETANTR) with loss of morphological but retained genetic key features during progression. Wöhrer et al, Acta Neuropathologica 2011, 122:787–90................................................................. 85 4. FISH-based detection of 1p 19q codeletion in oligodendroglial tumours: procedures and Protocols for neuropathological practice – a publication under the auspices of the Research Committee of the European Confederation of Neuropathological Societies. Wöhrer et al, Clinical Neuropathology 2011, 30:47–55................................................ 95 Curriculum vitae............................................................................................. 113